The referee blows the whistle, and Brentford runs out comfortable winners with a 2-0 scoreline.
They went closest in the first half as the game went to the break goalless, with Mbeumo fizzing a shot towards the top left corner, which Fabianski tipped round the post.
The Frenchman was the man to break the deadlock, though, after he cleverly was put through by Toney early into the second half.
Mbeumo shot the first time, firing past Fabianski to make it 1-0. Toney doubled his side’s advantage on 64 minutes when Mbeumo could hook the ball back across goal from a Henry cross.
The former Peterborough striker was there waiting and nodded home to make it 2-0.
The visitors tried to get back into the game late on but struggled to create much of note, with Benrahma sending a deflected effort just over in injury time against his former club.
The Bees defended well and saw out the remainder of the game to secure the three points.
BRENTFORD (4-5-1): David Raya; Kristoffer Ajer, Zanka, Ethan Pinnock, Rico Henry; Bryan Mbeumo, Christian Eriksen, Christian Norgaard, Vitaly Janelt, Yoane Wissa; Ivan Toney.
WEST HAM (4-2-3-1): Lukasz Fabianski; Vladimir Coufal, Craig Dawson, Kurt Zouma, Aaron Cresswell; Tomas Soucek, Declan Rice; Jarrod Bowen, Manuel Lanzini, Pablo Fornals; Michail Antonio.
Brentford, take the lead!!! Ajer takes the throw-in and finds Toney, who sidefoots the ball first-time to Mbeumo. The Frenchman then finishes past Fabianski to make it 1-0
Toney doubles the lead!!! Mbeumo does well to hook a Henry cross back over to his strike partner. Toney has to reach back for it a little but gets sufficient power and direction on the ball to send his header into the back of the net to make it 2-0.
So, what’s next?
The victory for Brentford lifts them to 13th position and crucially adds three points to the gap above the relegation zone, which now stretches to 12 points.
They travel to Watford next as they look to carry on this run that has seen them win four of their last five league matches.
Defeat for the Hammers means they lose pace with their rivals for the European qualification spots.
They will now turn their attention towards that crucial Europa League quarter-final second-leg against Lyon in midweek.
They will host relegation-threatened Burnley next in the league as they look to get back in the win column.